Neonatal sepsis: A review of the literature

Neonatal sepsis contributes significantly to neonatal morbidity and mortality is a major public health challenge around the world. Depending on mode of occurrence, distinction made between maternal-transmitted infection that acquired in postnatal period. Although etiologies maternally transmitted diseases are well understood, those infections variable depending epidemiology each hospital environment. On one hand, risk factors for maternal sepsis, prolonged premature rupture membranes, chorioamnionitis, bacteriuria mother during pregnancy. other prematurity, low birth weight, lack hygiene, invasive therapeutic interventions. The diagnosis based series anamnestic, clinical biological features. positive isolation germ by culture body sample (blood, cerebrospinal fluid, urine, etc.); its sensitivity leads use markers acute phase inflammation such as C-reactive protein, procalcitonin interleukins. New molecular biology techniques promising offer precise with rapid results. Empirical management function microbial ecology while definitive treatment guided results culture. This article presents essential elements understanding discusses new management. It offers thorough reading issue newborns.